- 30% to 80% of patients develop deep vein thromboses (DVT) following total joint arthroplasty
- Rivaroxaban superior to enoxaparin in efficacy following TKA
- Aspirin is inexpensive, easy to administer, reasonably well tolerated, requires no blood monitoring, and has an excellent safety profile. It is efficacious and safe agent for the prevention of VTE
- Tranexamic acid (TXA) is useful in controlling blood loss
- New Xa inhibitors-more bleeding
- No single standard recommendation available, but prophylaxis measures must
