- Modes of injury : stretching, compression and laceration
- Distal segment undergoes Wallerian degeneration
- Functional recovery during regeneration (in order)-sympathetic activity: Pain, Temperature sensation, Touch, Proprioception, Motor function
- Seddon and Sunderland classifications commonly used
- NCV and EMG are useful in diagnosing and assessing recovery
- Neurotmesis requires surgical end to end primary repair or nerve grafting
- Other treatment options include neurotization, nerve transfer, and tendon transfer
